%0 Online Multimedia %A Aron, Shaun %D 2018 %T Quality control and its importance in GWAS - Lecture 4 H3ABioNet 2018 GWAS Lecture series %U https://zivahub.uct.ac.za/articles/presentation/Quality_control_and_its_importance_in_GWAS_-_Lecture_4_H3ABioNet_2018_GWAS_Lecture_series/7068533 %R 10.25375/uct.7068533.v1 %2 https://zivahub.uct.ac.za/ndownloader/files/12996497 %K Genome Wide Association Studies %K Genotype calling %K H3Africa genotyping array %K African populations %K QC for GWAS %K Genome wide association study (GWAS) %K Sample Quality Control %K SNP Quality Control %K Population genomics %K Genotyping %K PLINK format %K Principal Component Analysis %K Low minor allele frequency %K Missingness %K GWAS workflow %K Discordant Sex information %K Nextflow %K Genotyping rate call %K Heterozygosity rate %K Related and duplicate individuals %K Identity by Descent %K Hardy Weinberg Equilibrium %K Bioinformatics %K H3ABioNet GWAS 2018 Lecture Series %K H3ABioNet %K Bioinformatics %K Biological Techniques %K Computational Biology %K Genetics %K Genomics %K Population, Ecological and Evolutionary Genetics %K Quantitative Genetics (incl. Disease and Trait Mapping Genetics) %X

Quality control and its importance in GWAS

In the fourth of a series of seven H3ABioNet online lectures for Genome Wide Association Studies (GWAS), the importance of doing good quality control for a GWAS will be discussed. The lecture will cover the types of errors one should control for, the specific bioinformatics tools used for quality control. Specific sample and SNP quality control steps that should be undertaken in a GWAS will be explored using specific examples.

%I University of Cape Town