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Data for "Intracellular mechanics and TBX3 expression jointly dictate the spreading mode of melanoma cells in 3D environments"

Version 3 2023-05-10, 10:43
Version 2 2022-06-17, 09:07
Version 1 2022-06-10, 13:00
dataset
posted on 2023-05-10, 10:43 authored by Ghodeejah Higgins, Faatiemah Higgins, Jade Peres, Dirk M. Lang, Tamer Abdalrahman, Muhammad H. Zaman, Sharon Prince, Thomas FranzThomas Franz
Quantitative data for Publication
G Higgins, F Higgins, DM Lang, T Abdalrahman, MH Zaman, S Prince, T Franz."Intracellular stiffness, mitochondrial activity and TBX3 expression jointly dictate the spreading mode of melanoma cells in 3D environments", bioRxiv, 2021

Three Excel files

File 1
File name: Microrheology Data
Data: Mitochondrial mean square displacement (MSD) and intracellular fluidity (α, Alpha)
Number of worksheets: 4
Worksheet name - Description of data
* D1 MSD - MSD data of isolated cells on Day 1
* D1 Alpha - Fluidity α of isolated cells on Day 1
* D7 MSD - MSD data of cell clusters on Day 7
* D7 Alpha - Fluidity α of cell clusters on Day 7

File 2
File name: Morphology Data
Data: Morphometric descriptors of cells, i.e. cell area, cell roundness
Number of worksheets: 1

File 3
File name: TBX3 Data
Data: Intracellular TBX3 expression levels
Number of worksheets: 1

Funding

the National Research Foundation of South Africa (grant number IFR14011761118 to TF)

South African Medical Research Council (TF and SP)

Cancer Association of South Africa (SP)

National Research Foundation of South Africa (grant number SRUG190306422357 to SP)

University of Cape Town (TF and SP)

History

Department/Unit

Department of Human Biology Faculty of Human Biology University of Cape Town

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    Biomedical Engineering

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