Data for identification of orthotropic material parameters for acute, necrotic, fibrotic and remodelling myocardial infarcts in the rat

dataset

posted on 2019-09-11, 14:10 authored by Mazin S Sirry, Laura Dubuis, Neil Hamer Davies, Jun Liao, Thomas FranzThomas Franz

The provided material represent the data used to identify the parameters of an orthotropic constitutive model for rat myocardial infarcts in the acute (0 day), necrotic (7 day), fibrotic (14 day) and remodelling phases (28 day). The study employed inverse methods top optimise the material parameters for Fung orthotropic material (ABAQUS CAE 6.12-2, Dassault Systèmes, Providence, RI, USA) utilizing experimental biaxial stress-strain data [1] and genetic algorithms toolbox in SCILAB 5.4 (Scilab Enterprises S.A.S, Versailles, France). The complete description of the methods can be found in the main article Sirry, MS, Dubuis L, Davies NH, Liao J, Franz T. Identification of orthotropic material parameters for acute, necrotic, fibrotic and remodelling myocardial infarcts in the rat. 2019, BIORXIV/2019/754754

Funding

Multiscale Modelling of Intramyocardial Stem Cell Therapies for Myocardial Infarction, UID92531, National Research Foundation, South Africa

Biomaterial Injection Therapies for Myocardial Infarction, Centre for High Performance Computing, Council for Scientific and Industrial Research, South Africa

Computational Mechanics and Electro-elasticity Towards Improved Understanding of the Biomechanics of Myocardial Infarction and the Development of Novel Therapies, Centre for High Performance Computing, Council for Scientific and Industrial Research, South Africa

Inter-university Cape Heart Group, South African Medical Research Council

History

Department/Unit

Biomedical Engineering Research Centre Division of Biomedical Engineering Department of Human Biology Faculty of Health Sciences University of Cape Town