Data for "An exploratory study on the role of the stiffness of breast cancer cells in their detachment from spheroids and migration in 3D collagen matrices"
Quantitative data for article G Higgins, JE Kim, J Ferruzzi, T Abdalrahman, T Franz, MH Zaman, Decreased cell stiffness facilitates cell detachment and cell migration from breast cancer spheroids in 3D collagen matrices of different rigidity. bioRxiv, 2020,
One Excel file with two spreadsheets: * Spreadsheet 'Spheroids in 2 mgml C': Data for experiments in collagen matrix with 2 mg/ml collagen concentration * Spreadsheet 'Spheroids in 4 mgml C': Data for experiments in collagen matrix with 4 mg/ml collagen concentration
Data in each spreadsheet includes mitochondrial MSD and intracellular fluidity at different delay times tau for cells at different distances from the cell spheroid, i.e. 0dc, 4dc and 6 dc (dc refers to cell diameter).
Funding
National Research Foundation of South Africa, grant IFR14011761118 to TF
South African Medical Research Council, grant SIR328148 to TF
Translational Research in Biomaterials
National Institute of Biomedical Imaging and Bioengineering
Biomedical Engineering Research Centre
Division of Biomedical Engineering
Department of Human Biology
Faculty of Health Sciences
University of Cape Town