Data_Manuscript P076.xlsx (3.36 MB)
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Decreased cell stiffness facilitates cell detachment and cell migration from breast cancer spheroids in 3D collagen matrices of different rigidity (data)

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posted on 23.03.2021, 05:49 by Ghodeejah Higgins, Jessica E. Kim, Jacopo Ferruzzi, Tamer Abdalrahman, Thomas FranzThomas Franz, Muhammad H. Zaman
Quantitative data for article G Higgins, JE Kim, J Ferruzzi, T Abdalrahman, T Franz, MH Zaman,
Decreased cell stiffness facilitates cell detachment and cell migration from breast cancer spheroids in 3D collagen matrices of different rigidity. bioRxiv, 2020,

One Excel file with two spreadsheets:
* Spreadsheet 'Spheroids in 2 mgml C': Data for experiments in collagen matrix with 2 mg/ml collagen concentration
* Spreadsheet 'Spheroids in 4 mgml C': Data for experiments in collagen matrix with 4 mg/ml collagen concentration

Data in each spreadsheet includes mitochondrial MSD and intracellular fluidity at different delay times tau for cells at different distances from the cell spheroid, i.e. 0dc, 4dc and 6 dc (dc refers to cell diameter).

Funding

National Research Foundation of South Africa (grant number IFR14011761118 to TF)

South African Medical Research Council (grant number SIR328148 to TF)

National Institutes of Health (grant numbers U01CA202123 and P01HL120839 to MHZ)

National Institutes of Health Training Grant at Boston University, T32 EB006359

History

Department/Unit

Department of Human Biology