University of Cape Town
Data_Manuscript P076.xlsx (3.36 MB)

Data for "An exploratory study on the role of the stiffness of breast cancer cells in their detachment from spheroids and migration in 3D collagen matrices"

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posted on 2022-04-25, 05:41 authored by Ghodeejah HigginsGhodeejah Higgins, Jessica E Kim, Jacopo Ferruzzi, Tamer Abdalrahman, Thomas FranzThomas Franz, Muhammad H Zaman
Quantitative data for article G Higgins, JE Kim, J Ferruzzi, T Abdalrahman, T Franz, MH Zaman,
Decreased cell stiffness facilitates cell detachment and cell migration from breast cancer spheroids in 3D collagen matrices of different rigidity. bioRxiv, 2020,

One Excel file with two spreadsheets:
* Spreadsheet 'Spheroids in 2 mgml C': Data for experiments in collagen matrix with 2 mg/ml collagen concentration
* Spreadsheet 'Spheroids in 4 mgml C': Data for experiments in collagen matrix with 4 mg/ml collagen concentration

Data in each spreadsheet includes mitochondrial MSD and intracellular fluidity at different delay times tau for cells at different distances from the cell spheroid, i.e. 0dc, 4dc and 6 dc (dc refers to cell diameter).


National Research Foundation of South Africa, grant IFR14011761118 to TF

South African Medical Research Council, grant SIR328148 to TF

Translational Research in Biomaterials

National Institute of Biomedical Imaging and Bioengineering

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Epithelial layer jamming in breast cancer cell migration

National Cancer Institute

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Physics of collective cellular migration in lung health and disease

National Heart Lung and Blood Institute

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Department of Human Biology