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Effects of BCG vaccination on donor unrestricted T cells in two prospective cohort studies
dataset
posted on 2022-04-07, 10:22 authored by Miguel Julio RodoMiguel Julio Rodo, Melissa Murphy, Anele GelaAnele Gela, Kate Hadley, Willem A. Hanekom, Mark Hatherill, Elisa NemesElisa Nemes, Thomas ScribaThomas Scriba, Libby Briel, Helen Veldtsman, Nondumiso KhombaThe data were generated to address whether BCG vaccination can modulate donor unrestricted T cells by performing immunological analyses using flow cytometry on PBMC samples collected from infants and adults in clinical studies completed previously (doi: 10.4049/jimmunol.1501996). The results are published in Gela (2021) - Effects of BCG vaccination on donor unrestricted T cells in humans.
`data_tidy_gela_durt.zip` is the source code to compile the R package `DataTidyGelaDURT`, which provides the following datasets:
- data_tidy_freq_ifng: Background-subtracted frequencies of IFNg+ cells for various subsets.
- data_tidy_freq: Frequencies of major cell populations
- data_tidy_hladr_adult: HLADR mean fluorescent intensity (MFI) by cell type for infants.
- data_tidy_hladr_infant: HLADR mean fluorescent intensity (MFI) by cell type for infants.
- data_tidy_mem: Frequency of memory phenotype relative to the parent population.
- Note that the package is also available at https://github.com/SATVILab/DataTidyGelaDURT (where any issues can be raised as well).
