age_inflammation_data.xlsx (1.9 MB)

Inflammatory determinants of differential tuberculosis risk in pre-adolescent children and young adults

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posted on 12.01.2021, 10:38 by Richard Baguma, Stanley Kimbung, Adam Penn-Nicholson, Thomas Scriba
The data provided here has been generated to investigate age-associated differences in immune responses of pre-adolescent children and young adults, with and without M. tuberculosis infection, as determined by an interferon-gamma (IFN-γ) release assay. A data compendium is provided that contains a priori soluble analytes that were quantified by Luminex bead arrays in supernatants from unstimulated or Mtb-stimulated whole blood, and mRNA transcripts that were quantified by microfluidic RT-qPCR in cryopreserved PBMC.

Funding

European and Developing Countries Clinical Trials Partnership (TA.2011.40200.010)

TBVAC2020 Consortium (H2020-PHC-643381)

History

Department/Unit

Department of Pathology

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South African Tuberculosis Vaccine Initiative (SATVI)

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