MOSAIC: A model to assess the cost-effectiveness of dexamethasone for admitted COVID-19 patients in South Africa

MODEL STRATEGIES
This model assesses costs and outcomes for admitted severe and critical Covid-19 patients from time of admission to discharge or death
Two competing strategies are modelled:
1. The "status quo" summarizes costs and outcomes for patients assuming usual care (no dexamethasone)
2. The "dexamethasone" comparator summarizes costs and outcomes for patients assuming usual care with dexamethasone at 6mg/day over 10 days
MODEL OUTCOMES
Cost: mean cost (general ward and ICU) per admitted patient from the health care provider's perspective
Health outcomes: mean DALYs and deaths per admitted patient
Other: mean ICU days and inpatient days per admitted patient