Studying the Role of Mechanical Properties of Cancer Cells in Tumour Detachment, Migration and Secondary Tumour Formation

<div>Data for chapters 3, 4 and 5 of PhD thesis.</div><div><br></div><div><div><u><b>CHAPTER 3</b></u></div><div>1 Data file</div><div><b>File name: Chapter_3_Data</b></div>Number of worksheets: 4</div><div>* Shape Statistics (area and circularity measurements) <br>* Migration Data <br>* WD Densometric Readings (western blot data) and <br>* Microrheology Data<br><br></div><div><u><b>CHAPTER 4</b></u></div><div>3 Data files</div><div><b>File 1: Chapter_4_Microrheology Data<br></b>Data: Mitochondrial mean square displacement (MSD) and intracellular fluidity (α, Alpha)<br>Number of worksheets: 4<br>Worksheet name - Description of data<br>* D1 MSD - MSD data of isolated cells on Day 1<br>* D1 Alpha - Fluidity α of isolated cells on Day 1<br>* D7 MSD - MSD data of cell clusters on Day 7<br>* D7 Alpha - Fluidity α of cell clusters on Day 7<br><br><b>File 2: Morphology Data</b><br>Data: Morphometric descriptors of cells, i.e. cell area, cell roundness<br>Number of worksheets: 1<br><br><b>File 3: Chapter_4_TBX3 Data</b><br>Data: Intracellular TBX3 expression levels<br>Number of worksheets: 1<br></div><div><br></div><div><u><b>CHAPTER 5</b></u></div><div>1 Data file</div><div><b>File name: Chapter_5_Data</b></div><div>Data: Mitochondrial MSD and intracellular power law coefficient alpha at different delay times tau for cells at different distances from the cell spheroid, i.e. 0dc, 4dc and 6 dc (dc refers to cell diameter).<br></div><div>Number of worksheets: 2</div><div>* Spreadsheet 'Spheroids in 2 mgml C': Data for experiments in collagen matrix with 2 mg/ml collagen concentration<br>* Spreadsheet 'Spheroids in 4 mgml C': Data for experiments in collagen matrix with 4 mg/ml collagen concentration<br></div>