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Khula South Africa Dataset: Cross-Validation Analysis Assessing Feasibility and Validity of Ultra- Low-Field MRI for Research on Antenatal Maternal Anaemia

dataset
posted on 2025-06-04, 07:20 authored by Jess RingshawJess Ringshaw, Michal ZieffMichal Zieff, Kirsty DonaldKirsty Donald

This dataset was used for a neuroimaging sub-study nested within Khula South Africa, a population-based birth cohort. Data supported cross-validation analyses demonstrating excellent correspondence between high-field (HF; 3T) and ultra- low-field (ULF; 64mT) volume estimates for infant brain regions associated with antenatal maternal anaemia. Overall, findings validated the use of ULF MRI for paediatric neuroimaging on anaemia and other relevant health priorities in Africa.

Funding

Characterizing the Impact of Antenatal Maternal Anaemia on the Child Brain using Magnetic Resonance Imaging (MRI) in Two South African Birth Cohorts

Wellcome Trust

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Wellcome Leap Inc. – Main Award

Wellcome Trust

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To demonstrate the ability to characterize fetal and infant neurodevelopmental outcomes associated with maternal iron deficiency using low field portable MRI

Bill & Melinda Gates Foundation

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History

Department/Unit

Division of Developmental Paediatrics Department of Paediatrics and Child Health Faculty of Health Sciences University of Cape Town