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Annotation of the H3Africa genotyping array

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posted on 2020-12-08, 09:42 authored by Ayton MeintjesAyton Meintjes, Nicola Mulder, Scott Hazelhurst, Gerrit Botha, Ananyo Choudhury, Mamana MbiyavangaMamana Mbiyavanga
<div>The linked site (chipinfo.h3abionet.org) serves annotation of the genotyping microarray designed by H3ABioNet and the H3Africa Consortium.<br></div><div><br></div><div>The content of the array includes:</div><ul><li>A backbone of probes, selected from existing Illumina pools, selected to maximise imputation of African populations</li><li>Novel variants, discovered from African sequence data</li><li>Markers requested by the H3Africa projects</li><li>Clinically relevant markers seen to be polymorphic in African datasets</li></ul>The site provides information on the content of the array, including.<br><ul><li>See if a specific marker is assayed on the array</li><li>View the coverage of a region</li><li>Visualise the orientation of the probe sequence of a probeset</li><li>See probe plots from a real dataset</li><li>View annotations</li></ul>

Funding

H3ABioNet: informatics solutions for H3Africa

National Human Genome Research Institute

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Computational Biology Group, IBMS

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