Population_structure_in_GWAS_Lecture_5.pdf (3.35 MB)
Population structure in GWAS - Lecture 5 H3ABioNet 2018 GWAS Lecture series
presentation
posted on 2018-09-11, 08:55 authored by Ananyo ChoudhuryThe fifth of a series of seven H3ABioNet online lectures for Genome Wide
Association Studies (GWAS) will introduce the concept of population
structure/stratification (PS) and suggest why it is critical to consider
PS in a GWAS. The lecture will begin by familiarizing the types of PS
that are encountered and explain the factors that could cause them to
appear in a GWAS dataset. It will then cover the methods that are
commonly used to identify PS in a dataset and finally discuss the
available computational approaches to correct for PS in a GWAS.
Funding
Research reported in this publication was supported by the National Human Genome Research Institute of the National Institutes of Health under Award Number U24HG006941. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
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Keywords
Genotyping experimentBioinformaticsGWAS studyPopulation geneticsPopulation genomicsPopulation structureH3ABioNet GWAS 2018 Lecture SeriesPopulation StructurePopulation stratificationAdmixtureAfrican PopulationsAfrican genomesBioinformaticsBiological TechniquesComputational BiologyGeneticsGenomicsPopulation, Ecological and Evolutionary Genetics
