Statistical models used for GWAS - Lecture 7 H3ABioNet 2018 GWAS Lecture series
presentationposted on 11.09.2018, 08:55 by Cheikh Loucoubar
Statistical models used for GWAS
The seventh and last lecture of the H3ABioNet 2018 GWAS lecture series will cover different types of GWAS depending on data designs: Population-based GWAS (for case/control design or for quantitative traits) and Family-based GWAS (for independent trio data or large pedigrees). This lecture will also provide an overview of test statistics for multi-marker association testing in both type of GWAS. It will discuss the problem of multiple testing, the principal of family wise error rate (FWER) and some proposed methods for P-values correction. The lecture will finally present a set of tools to perform GWAS and to represent results.