Liesl J Zühlke

Paediatric Cardiologist

Cape Town, South Africa

Publications

  • Primary prevention of acute rheumatic fever and rheumatic heart disease
  • Awareness, education, and advocacy
  • Digoxin and clinical outcomes in the Global Rheumatic Heart Disease Registry
  • Cardiovascular medicine and research in sub-Saharan Africa: challenges and opportunities
  • The Namibian Children’s Heart Project: a South–South partnership to provide cardiac care
  • Of Women, By Women, and For Women
  • Risk factors for COVID-19-related in-hospital mortality in a high HIV and tuberculosis prevalence setting in South Africa: a cohort study
  • Utility of Human Immune Responses to GAS Antigens as a Diagnostic Indicator for ARF: A Systematic Review
  • Health system costs of rheumatic heart disease care in South Africa
  • BS26 The partnerships in congenital heart disease in africa study (PROTEA): clinical characteristics and genetic findings from a South African congenital heart disease cohort
  • Managing Rheumatic Heart Disease in Pregnancy - A Practical Evidence-based Multi-Disciplinary Approach
  • Prof Lungile Pepeta (16 July 1974-7 August 2020)
  • Direct and indirect effects of the COVID-19 pandemic on children with cardiovascular disease
  • Transition to adulthood and transfer to adult care of adolescents with congenital heart disease: a global consensus statement of the ESC Association of Cardiovascular Nursing and Allied Professions (ACNAP), the ESC Working Group on Adult Congenital Heart Disease (WG ACHD), the Association for European Paediatric and Congenital Cardiology (AEPC), the Pan-African Society of Cardiology (PASCAR), the Asia-Pacific Pediatric Cardiac Society (APPCS), the Inter-American Society of Cardiology (IASC), the Cardiac Soc
  • Outpatient volumes and medical staffing resources as predictors for continuity of follow-up care during transfer of adolescents with congenital heart disease
  • Global prevalence of congenital heart disease in school-age children: a meta-analysis and systematic review
  • Global burden of cardiovascular diseases and risk factors, 1990-2019: update from the GBD 2019 study
  • Integrating the Prevention and Control of Rheumatic Heart Disease into Country Health Systems: A Systematic Review and Meta-Analysis
  • Rheumatic heart disease and COVID-19
  • Post cardiac surgery sternal wound sepsis burden, risk factors and outcomes at Red Cross War Memorial Children’s Hospital, Cape Town, South Africa: A five-year experience
  • Standard echocardiography versus handheld echocardiography for the detection of subclinical rheumatic heart disease: a systematic review and meta-analysis of diagnostic accuracy
  • SA Heart® Statement on COVID-19 and cardiovascular disease
  • Diseases, injuries, and risk factors in child and adolescent health, 1990 to 2017: findings from the Global Burden of Diseases, Injuries, and Risk Factors 2017 Study
  • P2427 The development of a computational fluid dynamics pipeline for the study of tetralogy of Fallot and coarctation of the aorta in a developing world context
  • Acute Rheumatic Fever and Rheumatic Heart Disease, E-Book
  • The INVICTUS rheumatic heart disease research program: rationale, design and baseline characteristics of a randomized trial of rivaroxaban compared to vitamin K antagonists in rheumatic valvular disease and atrial fibrillation
  • Difference in mortality among individuals admitted to hospital with COVID-19 during the first and second waves in South Africa: a cohort study
  • An investment case for the prevention and management of rheumatic heart disease in the African Union 2021–30: a modelling study
  • Global birth prevalence of congenital heart defects 1970-2017: Updated systematic review and meta-analysis of 260 studies
  • European society of cardiology: Cardiovascular disease statistics 2019
  • Global Representation of Heart Failure Clinical Trial Leaders and Collaborators: A Systematic Bibliometric Review 2000-2020
  • Global, regional, and national burden of congenital heart disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
  • Association of Novel Locus With Rheumatic Heart Disease in Black African Individuals: Findings From the RHDGen Study
  • Acute Rheumatic Fever and Rheumatic Heart Disease
  • A patient-specific CFD pipeline using doppler echocardiography for application in coarctation of the aorta in a limited resource clinical context
  • Medical education and training within congenital cardiology: current global status and future directions in a post COVID-19 world
  • Gender balance at the heart of science
  • Cardiopulmonary dysfunction in perinatally HIV-infected South African adolescents on antiretroviral therapy: baseline findings from the Cape Town Adolescent Antiretroviral Cohort
  • The inter-rater reliability and individual reviewer performance of the 2012 world heart federation guidelines for the echocardiographic diagnosis of latent rheumatic heart disease
  • Global epidemiology of valvular heart disease
  • Rationale and design of the African Cardiomyopathy and Myocarditis Registry Program: The IMHOTEP study
  • The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030
  • Rheumatic heart disease: current status of diagnosis and therapy
  • Endothelial Dysfunction in South African Youth Living With Perinatally Acquired Human Immunodeficiency Virus on Antiretroviral Therapy
  • Contemporary diagnosis and management of rheumatic heart disease: implications for closing the gap: a scientific statement from the American heart association
  • Discontinuity of Cardiac Follow-Up in Young People With Congenital Heart Disease Transitioning to Adulthood: A Systematic Review and Meta-Analysis
  • The RHD Action Small Grants Programme: Small Investment, Big Return!
  • European Society of Cardiology: cardiovascular disease statistics 2019 (executive summary)
  • Echocardiographic Findings in a Cohort of Perinatally HIV-Infected Adolescents Compared with Uninfected Peers from the Cape Town Adolescent Antiretroviral Cohort
  • Congenital heart disease in low-and lower-middle-income countries: current status and new opportunities
  • Targeted interventions reducing late maternal death due to heart failure
  • P1563 Reducing late maternal death due to cardiovascular disease by targeted interventions
  • The future of cardiovascular disease in South Africa and the role of the South African Heart Association
  • PO545 Pilot Testing the RHD Action Needs Assessment Tool In a Live Environment
  • PO456 Making Cardiac Surgery Feasible In African Countries: A Needs Assessment Questionnaire and Report of Experiences From Three Countries
  • Time to end Rheumatic Heart Disease: Lessons and opportunities from observational registries
  • Unraveling the role of healthcare system factors for continuing care of adolescents with congenital or rheumatic heart disease: Rationale and methods of the international Adole7C-project
  • The Reliability of the World Heart Federation Guidelines for the Echocardiographic Diagnosis of Rheumatic Heart Disease
  • European Society of Cardiology: cardiovascular disease statistics 2017
  • The Cape Town Declaration on access to cardiac surgery in the developing world
  • Prevention of infective endocarditis associated with dental interventions: position statement
  • PO649 Tools For Implementing Rheumatic Heart Disease Control Programmes 2nd Edition Update
  • Standard echocardiography versus handheld echocardiography for the detection of subclinical rheumatic heart disease: protocol for a systematic review
  • Reducing late maternal death due to cardiovascular disease-A pragmatic pilot study
  • Rheumatic heart disease worldwide: JACC scientific expert panel
  • Prevalence of rheumatic heart disease in Zambian school children
  • Trends and presentation patterns of acute rheumatic fever hospitalisations in the United States
  • Erratum: Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017 (The Lancet (2018) 392 (10159)(1684--1735),(S0140673618318919),(10.1016/S0140-6736 (18) 31891-9))
  • Integrating the prevention and control of rheumatic heart disease into country health systems: A systematic review protocol
  • Making cardiac surgery feasible in African countries: Experience from Namibia, Uganda, and Zambia
  • Task Sharing in the Diagnosis, Prevention, and Management of Rheumatic Heart Disease: A Systematic Review
  • The Cape Town Declaration on Access to Cardiac Surgery in the Developing World
  • Erratum: Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017 (The Lancet (2018) 392(10159) (1736–1788)(S0140673618322037)(10.1016/S0140-6736(18)32203-7))
  • The Cape Town Declaration on Access to Cardiac Surgery in the Developing World
  • Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: A systematic analysis for the Global Burden of Disease Study 2017
  • The Cape Town declaration on access to cardiac surgery in the developing world
  • The Cape Town declaration on access to cardiac surgery in the developing world
  • The Cape Town declaration on access to cardiac surgery in the developing world
  • Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017
  • Rheumatic heart disease patient event
  • The Cape Town Declaration on access to cardiac surgery in the developing world
  • Acquired heart disease in low-income and middle-income countries
  • A comprehensive needs assessment tool for planning RhD control programs in limited resource settings
  • Time to tackle rheumatic heart disease: data needed to drive global policy dialogues
  • Epidemiology of pharyngitis as reported by Zambian school children and their families: implications for demand-side interventions to prevent rheumatic heart disease
  • Task sharing to improve the prevention, diagnosis and management of rheumatic heart disease: a systematic review protocol
  • The African context of the Cape Town Declaration
  • Multisystem impairment in South African adolescents with Perinatally acquired HIV on antiretroviral therapy (ART)
  • Inter-rater and intra-rater reliability and agreement of echocardiographic diagnosis of rheumatic heart disease using the World Heart Federation evidence-based criteria
  • Pediatric systemic lupus erythematosus patients in South Africa have high prevalence and severity of cardiac and vascular manifestations
  • Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017
  • Participation in research improves overall patient management: insights from the Global Rheumatic Heart Disease registry (REMEDY)
  • Child and adolescent health from 1990 to 2015: findings from the global burden of diseases, injuries, and risk factors 2015 study
  • Infective endocarditis in infants and children in the Western Cape, South Africa: a retrospective analysis
  • Rheumatic fever and rheumatic heart disease: facts and research progress in Africa
  • Global unmet needs in cardiac surgery
  • Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016
  • Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990--2017: a systematic analysis for the Global Burden of Disease Study 2017
  • Prevention and control of rheumatic heart disease: Overcoming core challenges in resource-poor environments
  • Moving ahead: building a strong network among female cardiovascular clinician scientists and researchers in Africa
  • Rheumatic heart disease in Africa: the Mosi-o-Tunya call to action.
  • Pregnancy outcome in women with pulmonary hypertension: the Cardiac Disease in Maternity Groote Schuur Cohort Study
  • PM276 The Global Rheumatic Heart Disease Study (Remedy)--Data From Sudan
  • Academic-pharma partnerships in global health: lessons from Zambia and South Africa
  • Outcomes of asymptomatic and symptomatic rheumatic heart disease
  • Automated signal quality assessment of mobile phone-recorded heart sound signals
  • Acute rheumatic fever and rheumatic heart disease
  • The life and the legacy of Hamilton Naki: Experimental heart transplant surgeon and teacher
  • Prevalence of rheumatic heart disease in 4720 asymptomatic scholars from South Africa and Ethiopia
  • PANPACH: The First Independent Paediatric Workshop of the Pan African Network for Paediatric and Congenital Heart (PANPACH)
  • Mobile phone-based rheumatic heart disease diagnosis
  • Pulmonary hypertension and pregnancy outcome: data from the cardiac disease in maternity groote schuur cohort study
  • Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: the Global Rheumatic Heart Disease Registry (the REMEDY study).
  • PS296 Task Shifting: Proficiency of General Radiography Technicians in Detecting Rheumatic Heart Disease
  • Cardiology-cardiothoracic subspeciality training in South Africa: a position paper of the South Africa Heart Association: cardiovascular topics
  • An open-access, mobile compatible, electronic patient register for rheumatic heart disease (‘eRegister’) based on the World Heart Federation’s framework for patient registers
  • Acquired heart disease
  • Mobile phone-based rheumatic heart disease diagnosis
  • Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: A systematic analysis for the Global Burden of Disease Study 2016
  • Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
  • Erratum: Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: The Global Burden of Disease Study 2015 (The Lancet HIV (2016) 3 (e361-e387) PII: S235230181630087X DOI: 10.1016/S2352-3018(16)30087-X)
  • Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016
  • Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: A novel analysis from the global burden of disease study 2015
  • Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
  • Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015
  • Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
  • Pre-conception counselling for key cardiovascular conditions in Africa: Optimising pregnancy outcomes
  • Seven key actions to eradicate rheumatic heart disease in Africa: The Addis Ababa communiqu
  • Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
  • Moving Forward the RHD Agenda at Global and National Levels
  • Erratum: Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015 (The Lancet (2016) 388(10053) (1775–1812)(S0140673616314702)(10.1016/S0140-6736(16)31470-2))
  • Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016
  • Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2015: the Global Burden of Disease Study 2015
  • Asymptomatic rheumatic heart disease in South African schoolchildren: implications for addressing chronic health conditions through a school health service: in practice
  • The health systems barriers and facilitators for RhD prevalence: an epidemiological meta-analysis from Uganda and Tanzania
  • Factors associated with long-term mortality after Fontan procedures: a systematic review
  • Epidemiology, health systems and stakeholders in rheumatic heart disease in Africa: a systematic review protocol
  • Clinical outcomes in 3343 children and adults with rheumatic heart disease from 14 low-and middle-income countries: two-year follow-up of the Global Rheumatic Heart Disease Registry (the REMEDY Study)
  • Evaluation of a focussed protocol for hand-held echocardiography and computer-assisted auscultation in detecting latent rheumatic heart disease in scholars
  • The natural history of latent rheumatic heart disease in a 5 year follow-up study: a prospective observational study
  • Feasibility of pulse oximetry pre-discharge screening implementation for detecting critical congenital heart lesions in newborns in a secondary-level maternity hospital in the Western Cape, South Africa: The ‘POPSICLe’study
  • Incidence, prevalence and outcomes of rheumatic heart disease in South Africa: a systematic review protocol
  • Preliminary consultation on preferred product characteristics of benzathine penicillin G for secondary prophylaxis of rheumatic fever
  • Status and challenges of care in Africa for adults with congenital heart defects
  • Prevalence of rheumatic heart disease among school children in Ethiopia: A multisite echocardiography-based screening
  • Predicting long-term mortality after Fontan procedures: a risk score based on 6707 patients from 28 studies
  • Effect of distance to health facility on the maintenance of INR therapeutic ranges in rheumatic heart disease patients from Cape Town: no evidence for an association
  • Incidence, prevalence and outcome of rheumatic heart disease in South Africa: a systematic review of contemporary studies
  • Group A streptococcus, acute rheumatic fever and rheumatic heart disease: epidemiology and clinical considerations
  • Prevention of infective endocarditis associated with dental interventions: South African Heart Association position statement, endorsed by the South African Dental Association
  • Letter to the editor
  • Successes, failures, challenges and ground-breaking research: messages from the 6th World Congress of Paediatric Cardiology and Cardiac Surgery.
  • Management and prevention of rheumatic heart disease
  • Clinical manifestations and diagnosis of rheumatic heart disease
  • Cardiovascular and Metabolic Disease Research South African Medical Research Council
  • Development of the vanguard demonstration site for RHD screening among school-aged learners in the Western Cape, South Africa
  • Computer-assisted auscultation as a screening tool for cardiovascular disease: a cross-sectional study
  • Focus on 2007: a clinical audit of the Red Cross War Memorial Children's Hospital Paediatric Cardiac Surgery Programme
  • PROTEA, A southern African multicenter congenital heart disease registry and biorepository: Rationale, design, and initial results
  • Paediatric cardiac services in South Africa
  • Drugs for the paediatric heart
  • Preventing and managing cardiac disease in maternity-a model of care in a low resource set up
  • Paediatric Inflammatory Multisystem Syndrome-Temporally associated with SARS CoV-2 (PIMS-TS)/Multisystem Inflammatory Syndrome in Children (MIS-C) Version 2
  • The challenge of screening for asymptomatic rheumatic heart disease in South Africa: asymptomatic rheumatic heart disease
  • Primary prevention for rheumatic fever: Progress, obstacles, and opportunities
  • Rheumatic heart disease and the ASAP programme: Fresh insights into an old disease
  • Refractory, missed and severe Kawasaski disease: diagnostic and therapeutic challenges: case report
  • Rationale and design of a Global Rheumatic Heart Disease Registry: the REMEDY study
  • The second rheumatic heart disease forum report
  • The importance of awareness and education in prevention and control of RHD
  • Estimates of the global burden of rheumatic heart disease
  • Echocardiographic screening for subclinical rheumatic heart disease remains a research tool pending studies of impact on prognosis
  • Echocardiographic screening for rheumatic heart disease: issues for the cardiology community
  • Challenges and opportunities in paediatric cardiac services: Time for action
  • A review of the practice of a staged approach for biventricular repair in Red Cross Children's Hospital over the past six years: is the placement of a pulmonary artery band safer in perceived high-risk cases?
  • Of lice and men: A case of Bartonella quintana
  • World Heart Federation criteria for echocardiographic diagnosis of rheumatic heart disease - an evidence-based guideline
  • The Rheumatic Heart Disease Global Registry (REMEDY) study: preliminary report
  • Global research priorities in rheumatic fever and rheumatic heart disease
  • Two unusual cases of purulent pericarditis
  • Ortner syndrome
  • The incidence of the 22q11. 2 deletion syndrome in children referred to the Cardiology Service at the Red Cross Children's Hospital, Cape Town, South Africa: a prospective study
  • The burden of cardiovascular disease in sub-Saharan Africa: correspondence
  • Successes, failures, challenges and ground-breaking research: messages from the 6th World Congress of Paediatric Cardiology and Cardiac Surgery: cardio news
  • Is it time for developing countries to adopt neonatal pulse oximetry screening for critical congenital heart disease?: commentary
  • Management of atrio-ventricular septal defects in a developing country: an institutional experience
  • The role of echocardiography in diagnosing carditis in the setting of acute rheumatic fever
  • Continued Challenge of Rheumatic Heart Disease: The Gap of Understanding or the Gap of Implementation?
  • Alcapa: From critical to cured
  • Rheumatic fever and rheumatic heart disease: where are we now in South Africa?: ASAP programme
  • The promise of computer-assisted auscultation in screening for structural heart disease and clinical teaching
  • Signal quality classification of mobile phone-recorded phonocardiogram signals
  • Pulmonary artery banding: still a valuable option in developing countries?
  • Spectrum of cardiac disease in maternity in a low-resource cohort in South Africa
  • The case for global investment in rheumatic heart-disease control
  • Congenital heart disease and rheumatic heart disease in Africa: recent advances and current priorities
  • Rheumatic fever: neglected again
  • The genetics of congenital heart disease: The role of advanced genomic approaches
  • PROTEA, A Southern African Multicenter Congenital Heart Disease Registry and Biorepository: Rationale, Design, and Initial Results
  • Societies of Futures Past: Examining the History and Potential of International Society Collaborations in Addressing the Burden of Rheumatic Heart Disease in the Developing World
  • Secondary antibiotic prophylaxis for latent rheumatic heart disease
  • Understanding the local and international stakeholders in rheumatic heart disease field in Tanzania and Uganda: A systematic stakeholder mapping
  • Data independent acquisition mass spectrometry in severe Rheumatic Heart Disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases
  • How do we measure the implementation of the World Health Assembly resolution on rheumatic fever and rheumatic heart disease in African countries? Rationale and design of an evidence-based scorecard
  • Health trends, inequalities and opportunities in South Africa’s provinces, 1990–2019: findings from the Global Burden of Disease 2019 Study
  • Rheumatic Heart Disease Worldwide
  • Rheumatic Heart Disease: The time has come.
  • Child and adolescent health from 1990 to 2015: findings from the global burden of diseases, injuries, and risk factors 2015 study.
  • Prevention of infective endocarditis associated with dental interventions
  • Global leadership in paediatric and congenital cardiac care: “global health advocacy, lift as you rise – an interview with Liesl J. Zühlke, MBChB, MPH, PhD”
  • The Clinical Features and Estimated Incidence of MIS-C in Cape Town, South Africa
  • Outcomes after Bidirectional Glenn Shunt in a Tertiary Pediatric Hospital in South Africa
  • Outcomes after Bidirectional Glenn Shunt in a Tertiary-Care Pediatric Hospital in South Africa
  • Health trends, inequalities and opportunities in South Africa’s provinces, 1990–2019: findings from the Global Burden of Disease
  • Health trends, inequalities and opportunities in South Africa’s provinces, 1990–2019: findings from the Global Burden of Disease 2019 study

Liesl J Zühlke's public data