Mark Engel

Associate Professor

Cape Town

Publications

  • Is the introduction of violence and injury observatories associated with a reduction in violence-related injury in adult populations? A systematic review and meta-analysis
  • Burden of pneumocystis pneumonia in HIV-infected adults in sub-Saharan Africa: A systematic review and meta-analysis
  • Seven key actions to eradicate rheumatic heart disease in Africa: the Addis Ababa communique
  • Data Resource Profile: Cardiovascular H3Africa Innovation Resource (CHAIR)
  • Regional Patterns and Association Between Obesity and Hypertension in Africa Evidence From the H3Africa CHAIR Study
  • Reducing the Burden of Rheumatic Heart Disease: Prevalence of Group a Streptococcus emm Clusters in Africa Suggests Adequate Coverage by 30-Valent Vaccine
  • Prevalence of group A Streptococcal infection in Africa to inform GAS vaccines for rheumatic heart disease: A systematic review and meta -analysis
  • Correction: Rationale and design of the African group A streptococcal infection registry: The AFROStrep study (BMJ Open (2016) 6, (e010248))
  • Integrating the prevention and control of rheumatic heart disease into country health systems: A systematic review protocol
  • The effectiveness of peer and community health worker-led self-management support programs for improving diabetes health-related outcomes in adults in low- and-middle-income countries: A systematic review
  • Erratum for Barth et al., "Molecular Epidemiology of Noninvasive and Invasive Group A Streptococcal Infections in Cape Town"
  • Parents of children with disabilities: A systematic review of parenting interventions and self-efficacy
  • Rationale and design of the African group A streptococcal infection registry: the AFROStrep study
  • Factors associated with long-term mortality after Fontan procedures: a systematic review
  • Invasive and non-invasive group A β-haemolytic streptococcal infections in patients attending public sector facilities in South Africa: 2003–2015
  • Epidemiology of pharyngitis as reported by Zambian school children and their families: implications for demand-side interventions to prevent rheumatic heart disease
  • The Health Systems Barriers and Facilitators for RHD Prevalence: An Epidemiological Meta-Analysis From Uganda and Tanzania
  • The Cape Town Clinical Decision Rule for Streptococcal Pharyngitis in Children
  • Predicting long-term mortality after Fontan procedures: A risk score based on 6707 patients from 28 studies
  • Prevalence and risk factors of latent tuberculosis infection in Africa: a systematic review and meta-analysis protocol
  • Asymptomatic rheumatic heart disease in South African schoolchildren: Implications for addressing chronic health conditions through a school health service
  • Participation in research improves overall patient management: insights from the Global Rheumatic Heart Disease registry (REMEDY)
  • Evaluation of a focussed protocol for hand-held echocardiography and computer-assisted auscultation in detecting latent rheumatic heart disease in scholars
  • Treatment of oral fungal infections using photodynamic therapy: Systematic review and meta‐analysis
  • Clinical Outcomes in 3343 Children and Adults with Rheumatic Heart Disease from 14 Low-and Middle-Income Countries: Two-Year Follow-Up of the Global Rheumatic Heart Disease Registry (the REMEDY Study)
  • Seven key actions to eradicate rheumatic heart disease in Africa: The Addis Ababa communiqu
  • Group A Streptococcus, Acute Rheumatic Fever and Rheumatic Heart Disease: Epidemiology and Clinical Considerations
  • Preliminary consultation on preferred product characteristics of benzathine penicillin G for secondary prophylaxis of rheumatic fever
  • Task sharing to improve the prevention, diagnosis and management of rheumatic heart disease: A systematic review protocol
  • Rationale and design of the violence, injury and trauma observatory (VITO): The Cape Town VITO pilot studies protocol
  • Prevalence of rheumatic heart disease in Zambian school children
  • Standard echocardiography versus handheld echocardiography for the detection of subclinical rheumatic heart disease: Protocol for a systematic review
  • Effectiveness of control measures to prevent occupational tuberculosis infection in health care workers: A systematic review
  • Task Sharing in the Diagnosis, Prevention, and Management of Rheumatic Heart Disease: A Systematic Review
  • Epidemiology, health systems and stakeholders in rheumatic heart disease in Africa: A systematic review protocol
  • Prevalence of rheumatic heart disease among school children in Ethiopia: A multisite echocardiography-based screening
  • Burden of pneumocystis pneumonia in HIV-infected adults in sub-Saharan Africa: A systematic review and meta-analysis
  • A Comprehensive Needs Assessment Tool for Planning RHD Control Programs in Limited Resource Settings
  • Is computer-assisted instruction more effective than other educational methods in achieving ECG competence among medical students and residents? Protocol for a systematic review and meta-analysis
  • Digoxin and clinical outcomes in the Global Rheumatic Heart Disease Registry
  • Genetic variants in rheumatic fever and rheumatic heart disease
  • Systematic review and meta-analysis of the prevalence of Strep A emm clusters in Africa to inform vaccine development
  • Does genetics matter for disease-related stigma? The impact of genetic attribution on stigma associated with rheumatic heart disease in the Western Cape, South Africa
  • Systematic Review and Meta-analysis of the Prevalence of Group A Streptococcal emm Clusters in Africa To Inform Vaccine Development
  • Molecular Epidemiology of Noninvasive and Invasive Group A Streptococcal Infections in Cape Town
  • Modes of transmission and attack rates of group A Streptococcal infection: a protocol for a systematic review and meta-analysis
  • Rapid review of Global Strep A emm types
  • Association of Novel Locus With Rheumatic Heart Disease in Black African Individuals
  • An appraisal of laboratory models of androgenetic alopecia: A systematic review
  • Outcomes and complications of peripartum cardiomyopathy: protocol for a systematic review and meta-analysis
  • Rheumatic Fever: Neglected Again
  • Primary Prevention of Acute Rheumatic Fever and Rheumatic Heart Disease with Penicillin in South African Children with Pharyngitis: A Cost-Effectiveness Analysis
  • The Rheumatic Heart Disease Global Registry (REMEDY) study: preliminary report
  • Burden of pneumocystis pneumonia in HIV-infected adults in sub-Saharan Africa: protocol for a systematic review
  • Primary prevention of rheumatic fever in children: Key factors to consider Respone
  • Irlam et al. respond.
  • Erratum: (BMJ Open (2015) 5)
  • Incidence, prevalence and outcome of rheumatic heart disease in South Africa: A systematic review of contemporary studies
  • Tuberculosis surveillance in Cape Town, South Africa: an evaluation
  • Abnormal glucose metabolism in non-diabetic patients presenting with an acute stroke: prospective study and systematic review
  • Effect of distance to health facility on the maintenance of INR therapeutic ranges in rheumatic heart disease patients from Cape Town: no evidence for an association
  • Prevalence of group A streptococcal disease in North and Sub-Saharan Africa: a systematic review protocol
  • Group A streptococcal emm type prevalence among symptomatic children in Cape Town and potential vaccine coverage
  • Clinical and epidemiological aspects of streptococcus pyogenes pharyngitis and carriage in Africa.
  • Directly observed antiretroviral therapy: a systematic review and meta-analysis of randomised clinical trials
  • A cost-effective strategy for primary prevention of acute rheumatic fever and rheumatic heart disease in children with pharyngitis
  • Reference intervals for the echocardiographic measurements of the right heart in children and adolescents: a systematic review
  • The Effects of Angiotensin Converting Enzyme Inhibitors (ACE-I) on Human N-Acetyl-Seryl-Aspartyl-Lysyl-Proline (Ac-SDKP) Levels: A Systematic Review and Meta-Analysis
  • Is the introduction of violence and injury observatories associated with a reduction of violence in adult populations? Rationale and protocol for a systematic review
  • Genetic susceptibility to acute rheumatic Fever: a systematic review and meta-analysis of twin studies
  • Rheumatic heart disease in Africa: the Mosi-o-Tunya call to action
  • Rationale and design of a Global Rheumatic Heart Disease Registry: the REMEDY study
  • Mobile phone text messaging for improving the uptake of vaccinations: a systematic review protocol
  • An open-access, mobile compatible, electronic patient register for rheumatic heart disease ('eRegister') based on the World Heart Federation's framework for patient registers
  • The prevalence of type 2 diabetes among older people in Africa: a systematic review
  • N-acetylcysteine for non-paracetamol drug-induced liver injury: a systematic review protocol
  • Rheumatic fever and rheumatic heart disease: Where are we now in South Africa?
  • Research capacity. Enabling the genomic revolution in Africa
  • Primary prevention of acute rheumatic fever and rheumatic heart disease with penicillin in South African children with pharyngitis: a cost-effectiveness analysis
  • Prevalence of rheumatic heart disease in 4720 asymptomatic scholars from South Africa and Ethiopia
  • The prevalence of type 2 diabetes mellitus among older people in Africa: a systematic review study protocol
  • Burden of pneumocystis pneumonia in HIV-infected adults in sub-Saharan Africa: protocol for a systematic review.
  • Rheumatic fever: Neglected again
  • Re: Primary prevention of rheumatic fever in children: Key factors to consider
  • Updated model of group A Streptococcus M proteins based on a comprehensive worldwide study
  • Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: The Global Rheumatic Heart Disease Registry (the REMEDY study)
  • Letter to the editor
  • The burden of pertussis in low- and middle-income countries since the inception of the Expanded Programme on Immunization (EPI) in 1974: A systematic review protocol
  • Effectiveness of community-based peer-led diabetes self-management programmes (COMP-DSMP) for improving clinical outcomes and quality of life of adults with diabetes in primary care settings in low and middle-income countries (LMIC): A systematic review and meta-analysis
  • The natural history of latent rheumatic heart disease in a 5 year follow-up study: A prospective observational study
  • The burden of antenatal heart disease in South Africa: A systematic review
  • Mycobacterium w immunotherapy for treating pulmonary tuberculosis - A systematic review
  • A systematic and functional classification of Streptococcus pyogenes that serves as a new tool for molecular typing and vaccine development
  • The importance of awareness and education in prevention and control of RHD
  • The second rheumatic heart disease forum report
  • Health education interventions to raise awareness of rheumatic fever: a systematic review protocol.
  • Incidence, prevalence and outcomes of rheumatic heart disease in South Africa: A systematic review protocol
  • Rheumatic Fever: Neglected Again
  • The Rheumatic Heart Disease Global Registry (REMEDY) study: preliminary report
  • Primary prevention of rheumatic fever in children: Key factors to consider Respone
  • Mobile phone text messaging for improving the uptake of vaccinations: a systematic review protocol
  • Mycobacterium w immunotherapy for treating pulmonary tuberculosis - a systematic review
  • Investigation for a 30bp deletion in the EBV LMP oncogene in South African Hodgkin's disease
  • No evidence for an association between the mitochondrial variant T16189C and dilated cardiomyopathy: A systematic review and meta-analysis
  • Acute rheumatic fever surveillance in South Africa: An evaluation tool based on the CDC guidelines for evaluating public health surveillance systems
  • Genetic contribution to rheumatic fever: A systematic review and meta-analysis of twin studies
  • Prevalence of Group A -hemolytic Streptococcal Throat Carriage and Prospective Pilot Surveillance of Streptococcal Sore Throat in Ugandan School Children
  • Regional patterns and the association between obesity and hypertension in Africa: 30,044 participants from the H3Africa CHAIR study across 13 countries.
  • Is computer-assisted instruction more effective than other educational methods in achieving ECG competence amongst medical students and residents? A systematic review and meta-analysis
  • RHD Forum Meeting Report Writing Committee. The Second Rheumatic Heart Disease Forum Report.
  • Corticosteroids for tuberculous pleurisy
  • Conducting a meta-ethnography of qualitative literature: lessons learnt
  • Patient adherence to tuberculosis treatment: a systematic review of qualitative research
  • The mitochondrial DNA T16189C polymorphism and HIV-associated cardiomyopathy: a genotype-phenotype association study
  • Rheumatic Heart Disease: The time has come.
  • Detection of EBV in 48 cases of South African childhood Hodgkin's disease
  • Paediatric rhabdomyosarcoma: MyoD1 demonstration in routinely processed tissue sections using wet heat pretreatment (pressure cooking) for antigen retrieval
  • Epstein-Barr virus in Hodgkin's disease: Frequency of a 30-bp deletion in the latent membrane protein 1 (LMP-1) oncogene in South African patients
  • Improved prognosis of Epstein-Barr virus associated childhood Hodgkin's lymphoma: Study of 47 South African cases
  • Updated model of group A Streptococcus M proteins based on a comprehensive worldwide study.
  • Rheumatic Heart Disease: The time has come.
  • Long-awaited update on estimates of acute rheumatic fever in Africa
  • The incidence of sore throat and group A streptococcal pharyngitis in children at high risk of developing acute rheumatic fever: A systematic review and meta-analysis
  • No evidence for an association between the mitochondrial variant T16189C and dilated cardiomyopathy: A systematic review and meta-analysis
  • Epstein-Barr virus in Hodgkin's disease: Frequency of a 30-bp deletion in the latent membrane protein 1 (LMP-1) oncogene in South African patients
  • Investigation for a 30bp deletion in the EBV LMP oncogene in South African Hodgkin's disease
  • Prevalence of group A Streptococcal infection in Africa to inform GAS vaccines for rheumatic heart disease: A Systematic review and Meta-analysis.
  • Acute rheumatic fever surveillance in South Africa: An evaluation tool based on the CDC guidelines for evaluating public health surveillance systems
  • Factors associated with tuberculosis diagnosis and treatment delays in Middle East and North Africa: a systematic review.
  • A Patient-Specific CFD Pipeline Using Doppler Echocardiography for Application in Coarctation of the Aorta in Limited Resource Clinical Context.
  • The effectiveness of peer and community health worker-led self-management support programs for improving diabetes health-related outcomes in adults in low-and-middle-income countries: A systematic review.
  • Improved prognosis of Epstein-Barr virus associated childhood Hodgkin's lymphoma: study of 47 South African cases
  • Genetic contribution to rheumatic fever: A systematic review and meta-analysis of twin studies
  • Paediatric rhabdomyosarcoma: MyoD1 demonstration in routinely processed tissue sections using wet heat pretreatment (pressure cooking) for antigen retrieval
  • Prevalence of rheumatic heart disease in 4720 asymptomatic scholars from South Africa and Ethiopia
  • The Importance of Awareness and Education in Prevention and Control of RHD
  • Regional patterns and the association between obesity and hypertension in Africa: 30,044 participants from the H3Africa CHAIR study across 13 countries.
  • The burden of pertussis in low- and middle-income countries since the inception of the Expanded Programme on Immunization (EPI) in 1974: a systematic review protocol.
  • Regional Patterns and Association Between Obesity and Hypertension in Africa Evidence From the H3Africa CHAIR Study
  • Prevalence of group A β-hemolytic streptococcal throat carriage and prospective pilot surveillance of streptococcal sore throat in Ugandan school children
  • The burden of laboratory-confirmed pertussis in low- and middle-income countries since the inception of the Expanded Programme on Immunisation (EPI) in 1974: a systematic review and meta-analysis
  • Long-awaited update on estimates of acute rheumatic fever in Africa.
  • Prevalence and distribution of HPV infection and subtypes in oral squamous cell carcinoma in Africa: a systematic review protocol
  • Utility of Human Immune Responses to GAS Antigens as a Diagnostic Indicator for ARF: A Systematic Review
  • Understanding the local and international stakeholders in rheumatic heart disease field in Tanzania and Uganda: A systematic stakeholder mapping
  • Data independent acquisition mass spectrometry in severe Rheumatic Heart Disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases
  • Risk of immune reconstitution inflammatory syndrome with integrase inhibitors versus other classes of antiretrovirals
  • How do we measure the implementation of the World Health Assembly resolution on rheumatic fever and rheumatic heart disease in African countries? Rationale and design of an evidence-based scorecard
  • Primary prevention of acute rheumatic fever and rheumatic heart disease
  • International Travel-Related Control Measures to contain The Covid-19 Pandemic: An update to a Cochrane Rapid Review
  • Long-awaited update on estimates of acute rheumatic fever in Africa Comment
  • Long-awaited update on estimates of acute rheumatic fever in Africa.
  • A global perspective on the management and outcomes of peripartum cardiomyopathy: a systematic review and meta‐analysis

Mark Engel's public data